Chromonychia, caused by bacterial infection with P. aeruginosa.

What is the cause of the green colour of nails in subjects with pseudomona Infection

= Due to the pigment siderophore pyoverdin elborated by pseudomonas.

Passenger Leucocytes in platelets

Associated with

1. Febrile reactions
2. Immunomodulatory effects
3. Allo immunisation
4. Transfusion associated virus infection
   

Novel Hemostatic factors

1. Infusible platelet membranes
2. Thrombospheres
3. Liposome based agents
   

Platelet Derivatives

1. Platelet derived products - - Frozen platelets, Cold Liquid platelets, Photochemically treated platelets, Platelet derived micro spheres Culture derived platelets.
2. Lyophillised platelets
3. Platelet derived micro particles
   
4. Culture derived platelets
5. Platelet substitutes - Red cells with surface bound fibrin, Albumin coated micro-spheres, Liposome based agents
   

D/D Pediatric small round cell tumours of Bone and Soft tissue

1. PPNET
2. RMS
3. Neuroblastoma
4. DSRCT
5. Lymphoma
6. Malignant melanoma of soft part
7. Small cell osteosarcoma
8. Extrarenal monophasic Wilms
9. Extrarenal rhabdoid tumor
   

INVASIVE ASPERGILLOSIS

Risk factors for invasive Aspergillosis

1. Steroids
2. Chemotherapy resulting in severe neutropenia
3. Stem cell& solid organ transplantation
4. Late stages of AIDS
5. Chronic granulomatous disease.

TIgecycline

Indcations -- Skin and skin structure infections
- E Ffecalis,Staph Aureus,Strep Agalactice,Spyogenes,B Fragilis
Complicated intra abdominal infection due to
- E Coli,Klebsiella,E Fecalis,S Aureus,Bfragilis,B pERFRINGENS